
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

With children dying at an alarming rate at a Texas hospital, authorities narrow down their probe to one nurse, but the murder weapon remains elusive.

Time of death becomes pivotal when a pregnant woman is found murdered in her air-conditioned bedroom.

When a doctor's wife disappears, investigators use concrete from the doctor's yard and the recollections of a child to determine what happened.

A couple's murder leads investigators into the world of white supremacists and a string of hate crimes.