
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

When a human skeleton is found on marshland and determined to be at least 18 months old, a computer consultant gives her a face and name.

A cunning serial rapist who leaves no decisive evidence forces investigators to rely on geographical profiling in their search for an identity; DNA from a cigarette butt may provide the final piece of evidence needed to catch the suspect.

A killer places all the incriminating evidence to the murder in a plastic bag, hoping it will float down the river.

A mother and her two young daughters are found brutally murdered and sexually violated; the crime scene has no shortage of evidence, but investigators cannot find a conclusive link to their prime suspect.