
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.
A 2-year-old boy's brain seizures and breathing problems baffle doctors until they learn the mother exhibits signs of Munchausen syndrome by proxy, a rare condition that led her to physically abuse her son and contributed to her daughter's death.
Two years after an 18-year-old's murder in Albion, Mich., a tiny drop of blood and burned bones lead police to her killers.
A mother claims that an intruder murdered her two sons, but lacking a motive, police use blood-spatter analysis and behavioral profiling to reconstruct a different scenario.
A routine missing persons report leads Texas police to discover a deadly love triangle; evidence found in a suspect's home matches the murder scene and leads to the indictment of the victim's girlfriend and her lover.