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Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.
S5, EP2 "Dew Process"
New evidence including fibers and weather patterns point to a different killer in the 1986 case of a Pennsylvania dentist's murdered wife.
S5, EP11 "Lasting Impression"
When the decomposed body of a young girl is discovered, police have no clues to her identity, but days earlier, a stabbing victim told them she thought she might have witnessed a murder.
S3, EP10 "Crime Seen"
Investigators reopen a case from 1984 involving the rape of a young Virginia woman when DNA testing refutes her identification of the rapist and calls everything into question, leading to the accused person's exoneration.
S7, EP12 "A Vow of Silence"
The disappearance of a mail-order bride proves suspicious when detectives learn that two of the Texas husband's previous wives had died in mysterious circumstances.
S14, EP21 "Expert Witness"
A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.
S14, EP20 "Funeral Services"
Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.
S14, EP19 "Skeleton Key"
A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.
S14, EP17 "Seeing Red"
A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.