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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S1, EP17 "The Tangerine Factor"
When Leonard finally works up the courage to ask Penny out on a date, they each turn to Sheldon for advice.
S2, EP1 "The Bad Fish Paradigm"
Penny's first date with Leonard goes awry; Penny finds Sheldon to be an unwilling confidant.
S12, EP16 "The D & D Vortex"
The gang uses deception and betrayal to make it to the one open seat at Wil Wheaton's celebrity Dungeons and Dragons game with William Shatner, Joe Manganiello, Kareem Abdul-Jabbar and Kevin Smith.
S12, EP17 "The Conference Valuation"
When Penny and Bernadette go to San Diego for a pharmaceutical sales convention, Wolowitz is left in charge of the kids; Sheldon finds a book about experimenting on kids.
