
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

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Howard and Bernadette struggle to leave Halley in day care; Bert introduces the gang to his new girlfriend, Rebecca.
Leonard is pleasantly surprised when Beverly comes to visit, and she's genuinely kind to him, until he finds out the real reason she's there; Denise and Stuart overstay their welcome at the Wolowitz house.
Sheldon takes acting lessons from Penny in hope of becoming a better teacher; Koothrappali fantasizes about his friend's girlfriend.
A wealthy donor makes Leonard question what he is willing to do for science.