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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S4, EP14 "The Thespian Catalyst"
Sheldon takes acting lessons from Penny in hope of becoming a better teacher; Koothrappali fantasizes about his friend's girlfriend.
S6, EP11 "The Santa Simulation"
During a game, Sheldon revisits Christmas memories; Amy, Penny and Bernadette look for a date for Koothrappali.
S6, EP12 "The Egg Salad Equivalency"
When Sheldon is accused of sexual harassment, he ends up getting Raj, Leonard and Wolowitz in trouble.
S6, EP13 "The Bakersfield Expedition"
As the guys don costumes and go on a road trip to a comic book convention, the ladies decide to stay home and try to interpret a comic book.
S12, EP24 "The Stockholm Syndrome"
Bernadette and Wolowitz leave their kids for the first time; Penny and Leonard try to keep a secret; Sheldon and Amy stick together; Koothrappali makes a new friend; the gang travels together into an uncharted future.
S12, EP23 "The Change Constant"
Sheldon and Amy await big news.
S12, EP12 "The Propagation Proposition"
Penny's ex-boyfriend Zack learns that he is infertile, so he asks Leonard for help; Koothrappali attempts to mend things with his ex-fiancee Anu.
S12, EP11 "The Paintball Scattering"
Penny and Leonard organize a paintball game, which results in mayhem when Sheldon becomes jealous of Amy; Koothrappali catches Anu with her ex-boyfriend; Stuart doesn't want to move in with Denise.