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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S6, EP3 "The Higgs Boson Observation"
Amy feels threatened by Sheldon's new assistant; Wolowitz starts to feel the pressures of being in space.
S6, EP4 "The Re-Entry Minimization"
Wolowitz's return from space isn't all he expected; game night becomes a gender war.
S6, EP5 "The Holographic Excitation"
The gang heads to Stuart's comic book store to celebrate Halloween; Leonard uses science to seduce Penny.
S6, EP6 "The Extract Obliteration"
A game threatens Sheldon's relationship with Stephen Hawking; Penny secretly signs up for a college class.
S12, EP1 "The Conjugal Configuration"
Sheldon and Amy's honeymoon runs aground in New York; Penny and Leonard discover they are uncomfortably similar to Amy's parents; Koothrappali insults physicist Neil deGrasse Tyson and starts a Twitter war.
