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The Big Bang Theory
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S2, EP11 "The Bath Item Gift Hypothesis"
Penny starts dating Leonard's handsome colleague; Leonard and his friends are tortured by Sheldon's obsession with gift-giving etiquette.
S10, EP11 "The Birthday Synchronicity"
While Howard and Bernadette welcome their new baby into the world, Amy celebrates her own birthday with Sheldon.
S3, EP11 "The Maternal Congruence"
Leonard is horrified when his mother (Christine Baranski) visits.
S7, EP8 "The Itchy Brain Simulation"
When a mistake comes to light, Sheldon makes Leonard walk a mile in his shoes; Penny decides to confront Raj's ex.