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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S4, EP12 "The Bus Pants Utilization"
Leonard's idea for a smartphone application causes friction in his friendship with Sheldon.
S4, EP13 "The Love Car Displacement"
Bernadette runs into her ex-boyfriend (Rick Fox) while attending a science event with Wolowitz.
S4, EP14 "The Thespian Catalyst"
Sheldon takes acting lessons from Penny in hope of becoming a better teacher; Koothrappali fantasizes about his friend's girlfriend.
S4, EP15 "The Benefactor Factor"
A wealthy donor makes Leonard question what he is willing to do for science.
S5, EP2 "The Infestation Hypothesis"
Amy is caught in the middle when Penny and Sheldon get into an argument over a pre-owned chair; Leonard tries to make his long-distance relationship more exciting.
S5, EP1 "The Skank Reflex Analysis"
Penny worries that she has ruined her relationship with her friends; Sheldon takes over the paintball team.