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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S12, EP6 "The Imitation Perturbation"
When Wolowitz dresses up as Sheldon for Halloween, Sheldon seeks retaliation at Leonard and Penny's Halloween party; Leonard is shocked when Penny doesn't remember their first kiss.
S6, EP1 "The Date Night Variable"
Raj faces his loneliness when his friends are out on dates; while in space, Wolowitz gets drawn into a fight between Bernadette and his mom.
S6, EP2 "The Decoupling Fluctuation"
Sheldon tries to intervene when he learns that Penny is thinking about breaking up with Leonard; Howard is picked on in space by the other astronauts.
S6, EP3 "The Higgs Boson Observation"
Amy feels threatened by Sheldon's new assistant; Wolowitz starts to feel the pressures of being in space.
S11, EP16 "The Neonatal Nomenclature"
When Bernadette won't go into labor, her friends try different tactics to get things started; Wolowitz confronts Bernadette after Amy accidentally reveals she's already chosen their son's name.
