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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S5, EP20 "The Transporter Malfunction"
When Penny buys Leonard and Sheldon "Star Trek" collectibles, Sheldon finds himself haunted by Mr. Spock; after a blind date, Raj believes he has met his future wife.
S2, EP8 "The Lizard-Spock Expansion"
Leonard inadvertently steals away the new woman Wolowitz thinks is the love of his life.
S5, EP12 "The Shiny Trinket Maneuver"
Amy is upset with Sheldon when he isn't impressed with her recent accomplishment; Howard struggles with Bernadette's aversion to children.
S5, EP13 "The Recombination Hypothesis"
Everything could change when Leonard spontaneously invites Penny to a romantic dinner.
S7, EP19 "The Indecision Amalgamation"
Raj struggles with guilt when he dates two women at once; Penny has a chance to play a part in a cheesy movie; Sheldon is torn between two gaming systems.
S7, EP18 "The Mommy Observation"
Sheldon is faced with a new reality when he visits his mom in Houston; a murder mystery party starts arguments.
S7, EP17 "The Friendship Turbulence"
Bernadette tries to negotiate peace between Sheldon and Wolowitz; Penny receives an embarrassing offer; Raj wants Amy to write to a woman on his behalf.
S7, EP16 "The Table Polarization"
When Leonard buys a dining room table, Sheldon re-evaluates the changes in his life; Bernadette is torn when Wolowitz gets the chance to go back to space.