
Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?

Leonard is pleasantly surprised when Beverly comes to visit, and she's genuinely kind to him, until he finds out the real reason she's there; Denise and Stuart overstay their welcome at the Wolowitz house.

Sheldon and Amy's honeymoon runs aground in New York; Penny and Leonard discover they are uncomfortably similar to Amy's parents; Koothrappali insults physicist Neil deGrasse Tyson and starts a Twitter war.

Sheldon is thrilled when Leonard starts dating a woman who meets Sheldon's stringent standards.

Sheldon and Amy await big news.