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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S5, EP4 "The Wiggly Finger Catalyst"
Raj wants a girlfriend, so Penny introduces him to a woman he can communicate with.
S5, EP5 "The Russian Rocket Reaction"
Wil Wheaton invites Leonard and Sheldon to a party at his house; Howard receives an opportunity.
S5, EP6 "The Rhinitis Revelation"
Sheldon finds himself competing with the gang for his mother's (Laurie Metcalf) attention when she visits.
S5, EP7 "The Good Guy Fluctuation"
An attractive comic book artist tests Leonard and Priya's relationship; Sheldon tries to scare his friends.
S12, EP2 "The Wedding Gift Wormhole"
Sheldon and Amy go crazy trying to figure out what "perfect gift" Leonard and Penny gave them for their wedding; Koothrappali decides to settle down and asks his father to arrange a marriage for him.
S12, EP1 "The Conjugal Configuration"
Sheldon and Amy's honeymoon runs aground in New York; Penny and Leonard discover they are uncomfortably similar to Amy's parents; Koothrappali insults physicist Neil deGrasse Tyson and starts a Twitter war.