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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S4, EP3 "The Zazzy Substitution"
When Sheldon searches for an alternative to human companionship, the guys become concerned.
S4, EP2 "The Cruciferous Vegetable Amplification"
Realizing he will not live long enough to download his consciousness into a robot body, Sheldon tries to extend his life span.
S12, EP7 "The Grant Allocation Derivation"
Leonard is caught between a rock and a hard place when he becomes responsible for distributing extra grant money; Bernadette turns the backyard playhouse into a hideaway to get away from her husband and kids.
S4, EP11 "The Justice League Recombination"
The guys try to bond with Penny's new boyfriend through a costume contest.