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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S12, EP1 "The Conjugal Configuration"
Sheldon and Amy's honeymoon runs aground in New York; Penny and Leonard discover they are uncomfortably similar to Amy's parents; Koothrappali insults physicist Neil deGrasse Tyson and starts a Twitter war.
S3, EP20 "The Spaghetti Catalyst"
Sheldon goes to extremes to keep Leonard and Penny happy when they stop speaking to each other.
S3, EP21 "The Plimpton Stimulation"
Sheldon invites a famous physicist to the apartment, and competes with Leonard for her attention.
S3, EP22 "The Staircase Implementation"
Leonard tells Penny about how he met Sheldon and what happened to the elevator.
S9, EP3 "The Bachelor Party Corrosion"
A flat tire during Leonard's bachelor party weekend in Mexico tests the guys' skills; Penny is compelled to tell her family that she and Leonard eloped.