
This animated series features the adventures of the Griffin family. Endearingly ignorant Peter and his stay-at-home wife, Lois, reside in Quahog, R.I., and have three kids. Meg, the eldest child, is a social outcast, and teenage Chris is awkward and clueless when it comes to the opposite sex. The youngest, Stewie, is a genius baby who is bent on killing his mother and destroying the world. Brian, the talking dog, keeps Stewie in check while sipping martinis and sorting through his own issues.
Meg plans her wedding to an unexpected Quahog resident; Peter's arms are torn off, and he is left with tiny hands that have yet to grow back.
When the family fails to help Lois with the Christmas shopping, she walks out on the family and the Griffins try to save Christmas on their own.
Lois and Peter are divided by differing views on who the next mayor of Quahog should be; upset at Lois' first choice, Peter seeks out the late Mayor Adam West's cousin, Wild Wild West.
When Peter makes it through a bad flu season without getting sick, the hospital asks him to volunteer as a nurse; he finds himself at a crossroads when his mortal enemy, the Giant Chicken, is admitted; Brian has an identity crisis.