
Dr. Temperance Brennan, a forensic anthropologist who works at the Jeffersonian Institution and also writes books, has an impressive ability to read clues from victims' bones. Consequently, law enforcement calls her to assist with investigations when remains are so badly decomposed, burned or destroyed that standard identification methods are useless. Brennan is teamed with Special Agent Seeley Booth, a former Army sniper, who mistrusts science and scientists when it comes to solving crimes but who has developed respect for Brennan, both professionally and personally.

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Brennan and Booth head to the Jersey Shore when decomposed remains are discovered; the team becomes fond of Booth's girlfriend; Angela tries to keep a secret.
When a skull and decomposing hands are found in a dumpster, the team searches for the rest of the victim's remains; Brennan agrees to shoot an episode of a children's show with professor Bunsen, "The Science Dude" Jude (David Alan Grier).
The skull of a promising young dancer is discovered at a construction site; Hannah's safety is jeopardized when an assignment takes her to a dangerous part of town.
Human remains from a 150-year-old slave ship surface; the investigation leads Booth and Brennan to a cruise where a murder victim is seen moments before his death.