
Dr. Temperance Brennan, a forensic anthropologist who works at the Jeffersonian Institution and also writes books, has an impressive ability to read clues from victims' bones. Consequently, law enforcement calls her to assist with investigations when remains are so badly decomposed, burned or destroyed that standard identification methods are useless. Brennan is teamed with Special Agent Seeley Booth, a former Army sniper, who mistrusts science and scientists when it comes to solving crimes but who has developed respect for Brennan, both professionally and personally.

Angela's psychic friend Avalon helps the team investigate when a psychic is found dead in the trunk of a tree; Booth and Brennan consider the pros and cons of Christine's imaginary friend.

The team investigates when a wealthy teacher is found dead in an abandoned bookstore; one of Brennan's interns teaches her to use Twitter.

The team investigates a local bakery after the body of an ex-con is found in pieces; Arastoo Vaziri considers visiting his dying brother in Iran, which causes friction between him and Cam.

The team investigates the death of a mini-golf superstar; Brennan worries her father is returning to a life of crime; Wendell asks Hodgins to help restore his girlfriend's family heirloom.