
Dr. Temperance Brennan, a forensic anthropologist who works at the Jeffersonian Institution and also writes books, has an impressive ability to read clues from victims' bones. Consequently, law enforcement calls her to assist with investigations when remains are so badly decomposed, burned or destroyed that standard identification methods are useless. Brennan is teamed with Special Agent Seeley Booth, a former Army sniper, who mistrusts science and scientists when it comes to solving crimes but who has developed respect for Brennan, both professionally and personally.

The body of a fraternity brother is discovered inside a rival school's mascot uniform; Booth tries to help his brother find a new job.

Brennan asks Booth to be the father of her child; Stewie Griffin (Seth MacFarlane) offers the couple advice.

When a body is discovered at a popular nightclub, everyone is a suspect.

Angela's psychic, Avalon Harmonia (Cyndi Lauper), alerts Brennan and Booth to the presence of a mass grave beneath a fountain.