
This long-running animated comedy focuses on the eponymous family in the town of Springfield in an unnamed U.S. state. The head of the Simpson family, Homer, is not a typical family man. A nuclear-plant employee, he does his best to lead his family but often finds that they are leading him. The family includes loving, blue-haired matriarch Marge, troublemaking son Bart, overachieving daughter Lisa and baby Maggie. Other Springfield residents include the family's religious neighbor, Ned Flanders, family physician Dr. Hibbert, Moe the bartender and police chief Clancy Wiggum.

Selma and Patty agree to stop smoking when they learn their father died of lung cancer; when Selma relapses, Patty becomes angry and moves in with Homer and Marge.

Through a series of YouTube recommended videos, the story of the rise and fall of the Simpson family vlog is revealed.

Homer ends up in the Springfield penitentiary after getting caught bribing an official; an FBI investigator (guest voice Jon Hamm) offers Homer a way to reduce his jail time.

Marge reconnects with a close group of mothers she used to be friends with; Bart tries to break up their group when his playdates stop being fun.