
Accidentally frozen, pizza-deliverer Fry wakes up 1,000 years in the future. He is taken in by his sole descendant, an elderly and addled scientist who owns a small cargo delivery service. Among the other crew members are Capt. Leela, accountant Hermes, intern Amy, obnoxious robot Bender and lobsterlike moocher "Dr." Zoidberg.
The crew is injected into Fry's body to fight off parasites he picked up from an egg-salad sandwich.
The guys are sentenced to death on Planet Amazonia by a race of giant women.
Bender meets a charming fembot in the Bending Factory when Farnsworth sends him there for rehabilitation.
Fry is strangely immune when flying brains invade Earth and reduce other humans to imbecility.