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Half-sisters Mona and Dee Dee are virtual strangers who have grown up separately and suddenly become neighbors in the same San Francisco apartment building. Mona is a budding music executive raised by her single mother to be free-spirited and independent. By contrast, younger Dee Dee is a privileged honor-roll collegian who grew up in a two-parent home but seeks her identity out of the shadow of her overbearing mother.
S2, EP2 "The Big Mis-Conception Episode"
Big Dee Dee and Dee Dee secretly take pregnancy tests; Mona accepts that Spencer is happy with his new girlfriend (Rowena King).
S2, EP3 "The Big Keep Your Eyes off My Prize Episode"
Phyllis and Big Dee Dee set their daughters up with the same aspiring politician (Anthony Montgomery).
S3, EP18 "The Big Doormat No More Episode"
When Dee Dee turns down Mona's request for a favor, Mona regrets telling her not to let people take advantage of her.
S2, EP4 "The Big Birth-Quake Episode"
An earthquake strikes on Mona's birthday, trapping Dee Dee and her pregnant mother together in the laundry room.
S4, EP22 "The Big Who You Gonna Call Episode"
Mona decides to take charge of her life and dates both Chase and Lorenzo; the decision causes complications; Dee Dee starts dating a health fanatic.
S4, EP21 "The Big Hide & Sneak Episode"
Mona sees a therapist to cope with the breakup and makes a discovery about Chase; Dee Dee tries to counsel Brett about staff relations at the office.
S4, EP20 "The Big Mother's What?! Episode"
After she breaks up with Chase, Mona's emotions get out of hand and jeopardize her career; Dee Dee suspects one of her clients is having an affair.
S4, EP19 "The Big Nervous Breakup Episode"
Following a brief encounter with her ex-boyfriend, Mona has provocative thoughts about other men; Big Dee Dee produces Adam's stand-up show.
