When Astor dreams of his mother, she tells him to go back to his sister; Anna returns home, broken but reunited with Astor; the siblings decide to set off for Italy, hopeful that someone has managed to find an antidote for the Red Fever.

Anna and Katia prepare for the wedding ceremony; Angelica falls into a deadly ambush; Katia decides to stay on at the villa while Anna sets off alone; Anna reaches Pietro and learns devastating news.

After the night's revelry, Anna searches for her brother, but Astor wants to stay with the blues; in attempting to escape, Anna is bitten by a viper and passes out; when she wakes up, she finds herself face to face with the Big Little Lady.

Astor is dipped in blue paint, making him one of the evil Angelica's followers; imprisoned in the supermarket basement, Anna tries to make an escape after Pietro comes looking for her, desperate to find her brother.

After taking care of Astor, Anna sets off in search of provisions and decides to go and look for Pietro, who lives on the shores of a lake; a gang of blues, drawn by a fire lit by Astor, turns up at the farm and forces Astor to Angelica's villa.