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Amber Guyger tried to convince the jury she was tired the night when she accidentally entered Botham Jean's apartment and shot him, thinking he was an intruder.

He abandoned his own kids and wasn't coming back. That's what the brother of Rosemarie Essa told jurors about the actions of Yazeed after police questioned him over her death. This emotional testimony came on Dominic DiPuccio's second day on the stand. The Defense questioned him under cross-examination. DiPuccio recalled how Yazeed fled the country right at the time police and his family began to suspect he may have been involved in his sister's death.

The cross-examination was underway with the brother of Rosemarie Essa. Dominic DiPuccio chose to adopt her two children when Yazeed Essa abandoned them and fled to Lebanon after the police questioned him about Rosemarie's death. DiPuccio could be considered the State's key witness because he was the one who pointed police to the poisoned calcium pills. Under cross-examination, Yazeed's lawyer tried to discredit him in the eyes of the jury.

The legal team for Yazeed Essa was not done questioning his brother-in-law on the stand. Dominic DiPuccio recalled when Yazeed disappeared and abandoned his children, they searched his home, business, and computer looking for clues as to his whereabouts. The jury later heard about observations and comments made by the defendant after his wife, Rosemarie, died. On the stand was an ER processing secretary working the day Rosemarie was admitted. She confirmed her death was a coroner's case.

Cyanide poisoning was central to this case because that is what killed Rosemarie Essa. She had taken a calcium pill that was laced with cyanide. Jurors got a lesson on all things cyanide. On the stand was Don Whitworth, a cyanide expert for DuPont chemical company. He confirmed that cyanide can be found everywhere in nature including in the human body. According to a toxicology report, Rosemarie had a deadly amount of potassium cyanide, which ended her life.

Linda Yancey and day-laborer Marcial Cax-Puluc are shot in the Yancey basement; Derrick Yancey, a 17-year veteran, had a tearful tale of self-defense; but a trail of evidence forces investigators to take a closer look at one of their own.

In 2001, University of South Carolina student Shelton Sanders disappeared while planning a friend's bachelor party; he was never seen again; when evidence leads to an arrest, however, prosecutors are left with a tall task.

When Vicki Beckham was found dead in her car on the side of a mountain road, with very little evidence, police called it almost the perfect crime; but a series of clues blew the case open, taking them from a strip club bouncer to a Bishop's son.