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Indiana State at Purdue
NCAAFThe Sycamores host the Boilermakers in West Lafayette to open a Week 1 game. The visiting Boilermakers suffered a 56-3 loss to Indiana in their last season and hope to bounce back, while Indiana State was defeated by Murray State 31-17 in its finale.
Toledo at Michigan State
NCAAFToledo Rockets visit the Michigan State Spartans at Spartan Stadium to open the season. The home Spartans look to improve on a 4-8 finish in 2025, while the visiting Rockets targets early momentum coming off an 8-5 record last season.
Fresno State at 14 USC
NCAAFThe USC Trojans host the Fresno State Bulldogs in Los Angeles for a Week 1 game. Home USC looks to build on a 42-26 victory over the Spartans led by quarterback Jayden Maiava, while visiting Fresno State looks to build on an 18-3 last season win.
North Texas at 6 Indiana
NCAAFThe Mean Green play the Hoosiers at Memorial Stadium in Bloomington for a Saturday Week 1 opener. Indiana enters after finishing No. 1 in the final 2025 poll, while North Texas looks to improve upon a No. 24 rank finish from the previous year.
Ohio at Nebraska
NCAAFThe Nebraska Cornhuskers host the Ohio Bobcats at Memorial Stadium in Lincoln. Nebraska opens its 2026 campaign after concluding last fall with a 44-22 bowl loss to Utah, while Ohio begins the year following a 9-4 overall record in 2025.
North Texas at 6 Indiana
NCAAFSemana 1 del fútbol americano universitario de la NCAA 2026. North Texas se enfrenta a Indiana. Desde el Memorial Stadium, en Bloomington, Indiana.
Ball State at 1 Ohio State
NCAAFThe Ohio State Buckeyes host the Ball State Cardinals at Ohio Stadium for Week 1. National contender Ohio State welcomes their neighbor Ball State to the Horseshoe for a non-conference game to kick off their 2026 college football schedules.
Boise State at 2 Oregon
NCAAFThe Boise State Broncos meet the Oregon Ducks at Autzen Stadium for an NCAA football game. Boise State ended their 2025 season with a brutal 38-10 loss against Washington, while Oregon broke an eight-game win streak with a 56-22 loss against Indiana.
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7 Miami at 1 Ohio State
NCAAFThe No. 10 Miami Hurricanes face the No. 2 Ohio State Buckeyes at AT&T Stadium. This is a high-stakes College Football Playoff Quarterfinal matchup. Miami advanced after a gritty 10-3 road upset over No. 7 Texas A&M in the CFP First Round.
Massachusetts at Rutgers
NCAAFThe UMass Minutemen and the Rutgers Scarlet Knights meet for a Week 1 season opener at SHI Stadium. The Minutemen suffered a 0-12 winless record during their 2025 season and look for redemption. Rutgers lost to Penn State in their final 2025 game.
Eastern Illinois at Minnesota
NCAAFThe Eastern Illinois Panthers face the Minnesota Golden Gophers at Huntington Bank Stadium. The Panthers suffered a seven-game loss streak in their 2025 season, while the Golden Gophers won against the Lobos 20-17 on Dec. 26, 2025 in the Rate Bowl.
Alabama-Birmingham at Illinois
NCAAFThe UAB Blazers and the Illinois Fighting Illini battle at Gies Memorial Stadium. The Blazers won against the Golden Hurricanes, 31-24, in their final 2025 game. Illinois defeated Tennessee 30-28 in the Liberty Mutual Music City Bowl in 2025.
6 Indiana at 1 Ohio State
NCAAFThe nation's only two unbeaten programs face off in the Big Ten championship game as No. 2 Indiana plays No. 1 Ohio State for the CFP's top seed. The Buckeyes seek a record 25th outright conference crown. The Hoosiers have not won a title since 1967.