
After discovering that his late father has gone through most of the family fortune, Tod Stiles hits the title trans-America highway in his Corvette in search of adventure with friend Buz Murdock, a survivor of New York's mean streets. The two work odd jobs as they meet and interact with colorful characters and find themselves plunged into one situation after another, some of them romantic, some of them very dangerous. Later, Linc Case, a Vietnam war hero trying to find himself, takes over as Tod's travel companion.

A man (Buster Keaton) who believes he is a jinx proves himself when his brother (Joe E. Brown) is wrongly arrested; guest John Astin.

An aging former gangster, just released from prison, hires Tod and Buz when he feels that a person from his past is trying to kill him.

Buz vows to end the reign of a surfing "king" (Jeremy Slate) after seeing his callous reaction to a fellow surfer's senseless death.

After being the unwitting accomplice in a cruel practical joke, Buzz enlists Tod's aid to help the victim redeem himself.