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Growing up in racially segregated Birmingham, Alabama, during the 1960's, Rene and Mary Elizabeth manage to stick together despite community intolerance of "mixed" friendships. Many years later, following the death of her father, Rene returns home and reunites with Mary Elizabeth. The women realize that despite their career and family differences, they can help each other find happiness.
S4, EP5 "One Hour of Drama"
Mary Elizabeth and Rene are trapped in Rene's office with a parolee when a tornado strikes Birmingham.
S4, EP6 "No Place in This World"
M.E. and Collier deal with the loss of their home; Rene represents a homeless woman; high-school boys try to crash young Rene and M.E.'s sleepover.
S4, EP7 "Peace of Mind"
Joe is sued after saving a child's life; M.E. and Collier look for an apartment; young M.E., Rene and Collier take high-school aptitude tests.
S4, EP8 "The Contest"
M.E. and Collier move into their new apartment; Rene's ex-husband visits; Rene and Judge Terhune work together; young Rene runs for student council.
