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Mensa-fied best friends and roommates Leonard and Sheldon, physicists who work at the California Institute of Technology, may be able to tell everybody more than they want to know about quantum physics, but getting through most basic social situations, especially ones involving women, totally baffles them. How lucky, then, that babe-alicious waitress/aspiring actress Penny moves in next door. Frequently seen hanging out with Leonard and Sheldon are friends and fellow Caltech scientists Wolowitz and Koothrappali. Will worlds collide? Does Einstein theorize in the woods?
S3, EP15 "The Large Hadron Collision"
Leonard must choose who to bring with him when he goes to see the Large Hadron Collider on Valentine's Day.
S1, EP5 "The Hamburger Postulate"
Leonard, realizing his pursuit of Penny is fruitless, has an unexpected encounter with a fellow scientist (Sara Gilbert).
S8, EP21 "The Communication Deterioration"
The guys fight over what message Raj should write for NASA in case of alien contact; Penny has to decide between auditioning for a movie or keeping her pharmaceutical sales job.
S8, EP22 "The Graduation Transmission"
Wolowitz questions his engineering skills after he and Sheldon can't get a toy drone to fly; a canceled flight puts Leonard's plans in jeopardy; Raj sets his parents against one another after he's cut off financially.
