
Dr. Jason Bull is the charming and cocky founder of successful trial consulting firm Trial Analysis Corporation, where he and his team of experts employ psychology, human intuition and high-tech data to understand jurors, lawyers, witnesses and defendants, and construct effective narratives to help their clients win. Bull's team include his brother-in-law Benny, neurolinguistics expert Marissa, former detective Danny, hacker Cable, and Chunk, who helps perfect clients' appearances for trial. "Bull" is inspired by the early career of Dr. Phil McGraw, who also serves as executive producer.

Bull tries to help a CEO whose company is accused of killing an employee with its self-driving car, but a secret emerges that could sabotage a trial win.

An attorney for one of Bull's former clients asks him to consult on a couple's civil suit against a teacher who had a sexual relationship with their son; the trial strategy suffers a major setback when the teen switches to the teacher's side.

The wife of a man whom Danny helped imprison for manslaughter detonates a bomb at the TAC offices and takes the team hostage to force Bull to prove her husband's innocence.

When Bull handles the defense of a building owner accused of killing tenants by carbon monoxide poisoning, the case rocks Bull and the team to their core.