
The dedicated members of Squad 51 of the Los Angeles County Fire Department's newly created Paramedical Rescue Service take on a series of life-or-death challenges in this drama filmed in semi-documentary style. Partners John Gage and Roy DeSoto put their lives on the line to save people from all sorts of mishaps.

The paramedics hold a demonstration for student nurses, one of whom interests Gage; the hospital staff saves a robber and his victim.

Gage begins a rocky affair with a stewardess (Gretchen Corbett) who asked his and DeSoto's help with an in-flight heart-attack victim.

Gage resents media attention given to a paramedic (Gary Crosby) from another squad; Brackett clashes with a tycoon over a diagnosis.

A dangerous chemical injures a firefighter during a fire department experiment; a motorcycle daredevil and a hiker require rescue.