
Growing up in racially segregated Birmingham, Alabama, during the 1960's, Rene and Mary Elizabeth manage to stick together despite community intolerance of "mixed" friendships. Many years later, following the death of her father, Rene returns home and reunites with Mary Elizabeth. The women realize that despite their career and family differences, they can help each other find happiness.

Kelly is pregnant; Rene announces her plans to investigate rapes; young Rene and ME sort through boyfriend issues.

Mary Elizabeth and Collier use Grandma Otis' legacy to start a construction business; Michael continues to stalk Rene; young M.E. and Rene happen upon a KKK meeting.

Rene's campaign manager hires an image consultant; M.E. encourages Collier to deal with his anger over Kelly's pregnancy; young M.E. learns what Rene goes through to relax her hair.

Candidate Rene admits to drug use; Kelly's drama teacher asks M.E. to adapt part of her book for a school skit; young M.E. and Rene protest the demolition of Port Dixie.