
Widow Kate Bradley and her three daughters - Bobbie Jo, Billie Jo and Bettie Jo - run the Shady Rest Hotel, a small-town inn where city folks come to enjoy the quiet. Nothing much happens around Hooterville, so it's up to the girls to come up with their own schemes for fun.

Homer Bedloe returns to Hooterville with his son Homer Jr., who is a carbon copy of his dad.

Billie Jo discovers that her late father wanted her to be a doctor.

Bobbie Jo falls for Alan Landman (Dennis Hopper), a poet and beatnik.

Railroad executive Homer Bedloe tries once again to get rid of the Hooterville Cannonball, this time by getting Floyd and Charley to quit by harassment.