
Peter Parker is a very intelligent young man. But when Peter gets bitten by a radioactive spider during a school field trip to Oscorp, he develops spider-like powers including the ability to shoot webbing from his hands and to climb up walls. When tragedy strikes close to his home, Peter must decide how to come to terms with the momentous loss but also how he must adjust to his new job as a masked superhero. Peter will face all manner of villains and those looking to cause trouble as he attempts to rid his city of corruption.

Spider-Man, Miles Morales, Spider-Girl, Ghost Spider, Harry Osborn and Doc Ock must stop the Goblin King in his newly acquired Goblin Mech Suit before he destroys New York City.

In order for Spider-Man to defeat the Goblin King, he must first bring together Doc Ock, Spider-Girl, Ghost Spider, Miles Morales and Harry Osborn as a team.

As Spider-Man and Harry Osborn seek the Goblin King to determine who is behind the Goblin Mask, Spider-Man becomes concerned Harry is leading him into trap.

Spider-Man must team up with Spider-Girl, Ghost Spider, and Doc Ock to track down a new threat -- the mysterious Goblin Nation.