
Emergency room nurse Jackie Peyton does everything she can to provide her patients with the best care possible while navigating the waters of a crumbling health-care system. But she has a secret that is increasingly difficult to keep from people -- she relies on Vicodin and Adderall to get her through high-stress shifts at a New York hospital, where she isn't above bending the rules to keep things running smoothly in the face of indifferent doctors, penny-pinching bean counters and miles of bureaucratic red tape.

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A man is attacked by his date's ex-husband; Mrs. Akalitus takes charge of a foundling; O'Hara has a personal crisis.
Jackie discovers a new temp nurse is abusing drugs; Mrs. Akalitus continues to care for the foundling; Coop tells Eddie that Jackie has a child.
Jackie admits a dying patient she previously treated; O'Hara tells a sister Jackie's secrets; an organ donation form is forged.
Jackie uses an unusual ploy to get Coop off her back; O'Hara helps Jackie remove her wedding ring; Jackie begins mother-daughter dance lessons with Grace.