A women's health clinic in Philadelphia is the setting for this drama. While dealing with a number of medical issues, the show often revolves around the conflict between the clinic's directors: one a passionate advocate for patients and the other a more discipline-oriented doctor.

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The emergency room staff races to find what is wrong with several infants; a patient needing kidney transplant faces a tough moral decision.
Andy goes on vacation; a bodybuilder refuses a Caesarean section; a high-school basketball player has attention-deficit disorder.
Andy treats a judge for hearing loss; Lu and Ben's romance blossoms; Peter faces murder charges after a string of elderly deaths.
A breast cancer survivor develops a psychological disorder.