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Mystery writer and amateur detective Jessica Fletcher - a down-to-earth, middle-aged widow - ferrets out the criminals in idyllic Cabot Cove, Maine, which apparently is the murder capital of the United States for the show's 12-season run. Though while traveling, she uncovers a fair number of killers as well.
S1, EP17 "Tough Guys Don't Die"
Jessica cooperates with private detective Harry McGraw (Jerry Orbach), whose partner died while researching a murder trial.
S1, EP20 "Murder Takes the Bus"
Stranded at a roadside diner by a storm, bus passengers Jessica and Sheriff Tupper investigate the murder of a fellow traveler.
S1, EP21 "Armed Response"
Hospitalized in Dallas after an airport accident, Jessica endures the inconvenience of a leg cast to probe an in-patient murder.
S1, EP22 "Murder at the Oasis"
Jessica reunites with her college roommate at a desert resort and probes the murder of the woman's ex-husband.
S12, EP24 "Death by Demographics"
After a San Francisco radio station changes its music format from classical to rock, the promoter who engineered the switch dies and Jessica searches for the killer.
S12, EP23 "Mrs. Parker's Revenge"
While Jessica is in Atlanta to address mystery writers, a lethal virus is stolen from the Biological Research Institute.
S12, EP22 "What You Don't Know Can Kill You"
Seth's niece returns to Cabot Cove for her wedding only to have her groom die accidentally before the event.
S12, EP21 "Race to Death"
Jessica investigates when a wealthy yachtsman is murdered two days before a big race, and his rival's daughter is charged with the crime.
