
A dedicated group of forensic investigators at the Las Vegas Crime Lab works to solve often-grisly crimes in Sin City. Heading up the graveyard shift (an appropriate term in this case) is supervisor D.B. Russell, a "Left Coast" Sherlock Holmes who devours crime novels. Members of Russell's team include Julie Finlay, Nick Stokes, Sara Sidle (the team's moral compass), Greg Sanders and Morgan Brody. The investigative team works closely with Capt. Jim Brass -- a seasoned detective who is a protector of CSI -- Dr. Al Robbins -- medical examiner -- and quirky lab technician David Hodges. Previous leaders of the group include Gil Grissom and Dr. Ray Langston.

Grissom and Nick are called to identify a young woman and find her killer; Warrick and Sara investigate the shooting of a cop.

A quadruple homicide shatters the serenity of a quiet suburban neighborhood and Grissom's team sets out to discover the motive behind the bizarre murders.

A serial killer begins leaving clues to taunt Grissom; Warrick and Nick clash when they investigate a car accident.

The death of a first-class passenger on a flight to Las Vegas has Grissom and his team scrambling to examine the physical evidence and get testimony from the other passengers.