
A dedicated group of forensic investigators at the Las Vegas Crime Lab works to solve often-grisly crimes in Sin City. Heading up the graveyard shift (an appropriate term in this case) is supervisor D.B. Russell, a "Left Coast" Sherlock Holmes who devours crime novels. Members of Russell's team include Julie Finlay, Nick Stokes, Sara Sidle (the team's moral compass), Greg Sanders and Morgan Brody. The investigative team works closely with Capt. Jim Brass -- a seasoned detective who is a protector of CSI -- Dr. Al Robbins -- medical examiner -- and quirky lab technician David Hodges. Previous leaders of the group include Gil Grissom and Dr. Ray Langston.

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A man blames the death of his wife and daughter on anonymous e-mail threats; Grissom attends a transfer hearing.
A popular young singer is found dead outside an infamous Las Vegas nightclub, leading the CSI team to uncover a link between that crime and a murder 50 years earlier.
When the team discovers a connection between a new murder and a serial killer, Grissom secretly joins the class of a criminal pathologist (Laurence Fishburne) to help crack the case.
Grissom announces that he is leaving, which surprises and saddens the team, and Dr. Raymond Langston may take a permanent position in the group.