
A dedicated group of forensic investigators at the Las Vegas Crime Lab works to solve often-grisly crimes in Sin City. Heading up the graveyard shift (an appropriate term in this case) is supervisor D.B. Russell, a "Left Coast" Sherlock Holmes who devours crime novels. Members of Russell's team include Julie Finlay, Nick Stokes, Sara Sidle (the team's moral compass), Greg Sanders and Morgan Brody. The investigative team works closely with Capt. Jim Brass -- a seasoned detective who is a protector of CSI -- Dr. Al Robbins -- medical examiner -- and quirky lab technician David Hodges. Previous leaders of the group include Gil Grissom and Dr. Ray Langston.

The CSI team members investigate when a robbery and fatal shooting take place at a medical marijuana shop.

When a crime scene turns out to be contaminated with a deadly pathogen, Greg and Sara must be quarantined.

When a chemistry teacher's science experiment goes terribly wrong, the CSI team has suspicions of foul play.

While Morgan, Finlay and Sidle seek relaxation at a forensics conference, a mass shooting takes place on site.