
A dedicated group of forensic investigators at the Las Vegas Crime Lab works to solve often-grisly crimes in Sin City. Heading up the graveyard shift (an appropriate term in this case) is supervisor D.B. Russell, a "Left Coast" Sherlock Holmes who devours crime novels. Members of Russell's team include Julie Finlay, Nick Stokes, Sara Sidle (the team's moral compass), Greg Sanders and Morgan Brody. The investigative team works closely with Capt. Jim Brass -- a seasoned detective who is a protector of CSI -- Dr. Al Robbins -- medical examiner -- and quirky lab technician David Hodges. Previous leaders of the group include Gil Grissom and Dr. Ray Langston.

A journalist follows Russell and the team as they investigate a series of murders; while undercover, one team member is jeopardized.

The CSI team members search for Morgan Brody and Ellie Brass, who have been taken captive by a serial killer.

A murder and a robbery take place during a poker game with more than $1 million in chips on the table.

The team investigates when a fire at a music venue claims the lives several people, including two members of a band.