
Dr. Mark Sloan is chief of Internal Medicine at Community General Hospital -- and sometime consultant to the local police department. When he's drawn into a case, he combines sleuthing and medicine to solve the crime. That crime is usually one his detective son, Steve, is working on as a member of the local police department. Dr. Sloan's medical colleagues, including doctors Amanda Bentley, Jack Stewart and Jesse Travis, are also frequently drawn into his investigations.

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Mark's investigation of a murder at Community General has him looking for both the murderer and the victim.
An actress is accused of murdering her ex-husband even though she was in the hospital for plastic surgery at the time.
A bride murders her wealthy father and attempts to frame her stepmother for the crime in retaliation for being cut out of his will.
Mark intercepts a call from a kidnapper and witnesses the murder of the abducted child's father while trying to locate the boy.