
Dr. Mark Sloan is chief of Internal Medicine at Community General Hospital -- and sometime consultant to the local police department. When he's drawn into a case, he combines sleuthing and medicine to solve the crime. That crime is usually one his detective son, Steve, is working on as a member of the local police department. Dr. Sloan's medical colleagues, including doctors Amanda Bentley, Jack Stewart and Jesse Travis, are also frequently drawn into his investigations.

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Dr. Sloan's brother (Jerry Van Dyke) is admitted to the hospital and becomes a murder suspect when his roommate is found dead.
Mark and Steve enter the glamorous world of modeling to track down an unlikely killer after the murder of a private investigator.
Mark discovers a case of insurance fraud in the hospital when a hasty cremation follows the misidentification of a corpse.
After Mark is nearly killed by a bomb, Steve's protégé goes undercover to learn the terrorists' next target.