
Dr. Mark Sloan is chief of Internal Medicine at Community General Hospital -- and sometime consultant to the local police department. When he's drawn into a case, he combines sleuthing and medicine to solve the crime. That crime is usually one his detective son, Steve, is working on as a member of the local police department. Dr. Sloan's medical colleagues, including doctors Amanda Bentley, Jack Stewart and Jesse Travis, are also frequently drawn into his investigations.

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An overworked and tired Jesse witnesses the death of a patient, but when the body vanishes, not even Dr. Sloan believes him.
In an episode that elapses in real time, Mark and Steve must catch a serial killer in the hospital before the clock strikes nine.
When Jesse (Charlie Schlatter) rescues a beautiful woman (guest star Audie England), he inadvertently becomes the object of her deadly obsession. With Dick Van Dyke.
The high-pressure learning environment for the interns at the hospital claims Amanda's cousin, but Amanda believes his death is no accident.