
Dr. Mark Sloan is chief of Internal Medicine at Community General Hospital -- and sometime consultant to the local police department. When he's drawn into a case, he combines sleuthing and medicine to solve the crime. That crime is usually one his detective son, Steve, is working on as a member of the local police department. Dr. Sloan's medical colleagues, including doctors Amanda Bentley, Jack Stewart and Jesse Travis, are also frequently drawn into his investigations.

A famous chef is killed at a charity auction while eating one of his own creations, a dish poisoned by a competitor at a popular food network.

Mark investigates the death of a friend whom he soon discovers had not only two wives, but numerous girlfriends.

Mark investigates the murder of a woman who died due to a malfunction in the computer system in her home; Steve decides to find a place of his own.

A murder and attack at his beach house prompt Mark to investigate a hospital staff member who was having an affair with the deceased's young wife.