
After the unsolved murder of his wife, Adrian Monk develops obsessive-compulsive disorder, which includes his terror of germs and contamination. His condition costs him his job as a prominent homicide detective in the San Francisco Police Department, but he continues to solve crimes with the help of his assistant and his former boss.

Monk travels to Las Vegas when Capt. Stottlemeyer suspects foul play in the death of a casino owner's wife.

Monk unravels a mystery when a toddler finds a severed finger in a park.

When Monk investigates a death aboard a submarine, the vessel suddenly descends, trapping Monk and the crew underwater.

Monk appears to have met his match when a fellow detective shows up at a crime scene knowing all the answers.