
A Florida team of forensics investigators uses cutting-edge scientific methods and old-fashioned police work to solve crimes. Horatio Caine, a former homicide detective, heads a group of investigators who work crimes amid the steamy tropical surroundings and cultural crossroads of Miami.

The team searches for a group of video gamers that has started to play the game in real life, killing police officers, stealing evidence, raping women, and robbing a bank.

Horatio and his team investigate the murder of a suspected drug lord as one member of the group is arrested for buying marijuana.

When a female executive is shot at an afternoon concert, the evidence leads the team to suspect that the dreaded Mala Noche gang has struck again.

Evidence shows that a series of murders is linked to organized crime, but it also leads Horatio and the team to a pair of film students whose screenplay mirrors the details of the crimes.