
A Florida team of forensics investigators uses cutting-edge scientific methods and old-fashioned police work to solve crimes. Horatio Caine, a former homicide detective, heads a group of investigators who work crimes amid the steamy tropical surroundings and cultural crossroads of Miami.

A convicted murderer escapes and begins to kill again, and the assailant's original arresting officer, Mac Taylor (Gary Sinise), comes to help Horatio Caine recapture the felon.

Ryan's life is in jeopardy when the team is caught in the midst of a deadly divorce case.

The team searches for a group of video gamers that has started to play the game in real life, killing police officers, stealing evidence, raping women, and robbing a bank.

Horatio and his team investigate the murder of a suspected drug lord as one member of the group is arrested for buying marijuana.