
Tom Selleck stars as Frank Reagan, the New York Police Commissioner, and patriarch of the Reagan clan, a multigenerational family of cops. Frank's oldest son is Danny, a seasoned detective and Iraqi War veteran who occasionally uses dubious tactics to solve cases. Daughter Erin, the lone female, is an assistant district attorney. Fresh out of Harvard Law, Jamie is the youngest member and "golden boy" of the family. Jamie gave up a lucrative future in law to continue the family's tradition in police work, and is asked to participate in a secretive investigation that even his father does not know about.

Frank deals with a whistleblower, who claims to have evidence of abuse throughout the NYPD; Danny and Baez investigate a woman who was hit by a car.

Danny has to work with Anthony to find the killer of a witness; Robert Lewis tries to force Frank to publicly support the Attorney General's investigation into the use of excessive force by police.

A woman becomes the prime suspect in the murder of her ex-boyfriend; Eddie is jealous when Jamie allows a young woman to crash at his apartment; an off-duty sergeant fails to intercede during a robbery.

Frank is left with little information to find a missing boy when a conflicted priest refuses to break the seal of confession; Danny and Baez look into the death of a socialite with a secret life; Jamie and Eddie attend a wedding.