
An elite squad of FBI profilers analyzes the country's most-twisted criminal minds, anticipating the perpetrators' next moves before they can strike again. Each member of the "mind hunter" team brings his or her expertise to pinpoint predators' motivations and identify emotional triggers to stop them. The core group includes an official profiler who is highly skilled at getting into the minds of criminals, a quirky genius, the former media liaison who manages to adeptly balance family life and the job, and a computer wizard.

The team suspects Kate's niece and her friend were kidnapped by an online predator involved in sex trafficking and race to find them before they are hurt.

The BAU interviews candidates to take the opening left by Kate's departure; the team tracks a serial killer who leaves behind evidence that indicates a person intent on revenge.

The team must find the person responsible for a sarin gas attack on a Los Angeles bus before a larger incident occurs.

The team suspects a jilted unknown subject is responsible when brides are murdered on the eve of their nuptials.