
"Big Hero 6 The Series" takes place after the events of the film "Big Hero 6" and continues the adventures of 14-year-old tech genius Hiro Hamada. He is joined by the compassionate robot Baymax which is created by Hiro's brother, Tadashi. Hiro and Baymax are also joined by their friends, including Wasabi, Honey Lemon, Go Go and Fred, as they embark upon new high-tech adventures to protect their home from villains. Hiro also faces challenges with his everyday life, including his academic work and social tribulations.

Chief Cruz and the police get the upper hand in their battle with both villains and Big Hero 6 when they begin using Buddy Guardians, powerful new robots produced by Krei Tech.

Hiro and Baymax discover that Trina is trying to get revenge for Obake and cement his legacy by destroying the city; Big Hero 6 is forced to find a way to work with the police.

Hiro's friends show up late to a mission and his faith in them wavers; Hiro and Big Hero 6 try to stop Noodle Burger Boy and his new sisters.

Big Hero 6 responds to Richardson's every wish when he is made mayor for the day; Granville's three dogs go missing while under Hiro's watch.