
Four mature women live together in Miami and experience the joys and angst of their golden years; strong-willed Dorothy, spacey Rose, lusty Southern belle Blanche and matriarch Sophia, Dorothy's mom, occasionally clash but are there for one another in the end; after all, when the show's theme song is titled "Thank You for Being a Friend," the ladies have to remain friendly with one another.

Dorothy makes her ex-husband, Stanley Zbornak, jealous when she has an affair with his brother Theodore.

Blanche reunites with her daughter Rebecca after a four-year estrangement; Blanche wants to defend her from an abusive boyfriend.

Rose's cousin, Sven Lindstrom, arrives from Sweden and falls in love with Blanche.

Blanche and Rose despise one of Dorothy's friends, the novelist Barbara Thorndyke.