
Four mature women live together in Miami and experience the joys and angst of their golden years; strong-willed Dorothy, spacey Rose, lusty Southern belle Blanche and matriarch Sophia, Dorothy's mom, occasionally clash but are there for one another in the end; after all, when the show's theme song is titled "Thank You for Being a Friend," the ladies have to remain friendly with one another.

Dorothy and her former tennis rival play practical jokes during a reunion.

Dorothy makes her ex-husband, Stanley Zbornak, jealous when she has an affair with his brother Theodore.

Dorothy and Blanche try to help Rose overcome a 30-year dependency on prescription medication.

The women try to help a neighborhood couple, George and Renee Corliss, patch up their faltering marriage.