
Eagle-eyed technical experts prove there is no such thing as a perfect crime as they assemble the pieces every criminal leaves behind. Dramatic crime re-creations and, sometimes, part of the investigations are a staple of the series. Some of the re-creations include alternate versions of the crimes, which are disproved by science. The show's episodes follow each case from the initial investigation until it reaches its legal resolution.

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California police in 1957 search for a murderer, but the case goes cold; 50 years after a crime is committed, advances in computer technology determine the killer.
Investigators piece together tiny clues at the scene of a hit-and-run accident; their findings help to track down the offending driver.
Investigators determine what caused a house fire that killed an elderly couple and whether the victims' son is responsible.
When a young woman goes missing on the way to the train station, investigators use a strand of hair and a bloody pillowcase to find a suspect.